Showing posts with label Spanish flu. Show all posts
Showing posts with label Spanish flu. Show all posts

Wednesday, April 29, 2009

Swine Flu: Deadly Threat or Alarmism?















Well I see that Don Martin has swapped his fedora for a white coat....and declared that the swine flu outbreak is nothing to worry about.

It’s likely beyond containment now, but to describe the Mexican swine flu outbreak as a potential re-run of the Spanish influenza pandemic seems, subject to change without notice, wildly alarmist......Today’s swine flu is no 1918 influenza, so perish the comparison.

When in fact, although we shouldn't panic, we simply don't know enough to rule anything out.

What we do know is that patient zero got sick on April 2nd...and the first recorded fatality happened eleven days later.

Which means that the virus has been running wild in Mexico for at least a month. It has only just arrived here.

And we still don't know why so far it has only killed Mexicans.

Is it because there have been many more cases than reported...and there are some other underlying factors?

A couple of factors could be causing the greater death toll in Mexico, said Howard Markel, a physician and director of the Center for the History of Medicine at the University of Michigan.

"They may have had cases for several months now and probably have a greater number of people who have the disease, probably tens of thousands," he said.

Also, he said, the people who have died in Mexico could have had what he called "another co-factor," such as taking medicine or having pre-existing infections that would make them more vulnerable. It's also possible, he said, that those who died had an underlying genetic predisposition or condition.

Is it because they were poor?

Julio Frenk, former health minister of Mexico and now dean of the Harvard School of Public Health, holds an opposing view: The disease could be killing people who are not healthy because of their living conditions.

"There could also be some elements in the host," he said. "These are poor people. Maybe their immune response is not as efficient. So we're going to have to just keep trying to understand why this difference and whether that continues as the epidemic unfolds."


Or is it just the first relatively mild wave of what could become a deadly pandemic? Just like the one that broke out in the Spring of 1918. But didn't turn into an agent of mass murder until August....when the second wave hit.












The bottom line: We still don't know anything about this new virus or where it's going.

Panic is bad, but so is denial.

Idiocy is WORSE.

“It is a tragedy only for people living ... in slums in Asia or Mexico. But will the honeymoon couple from Edinburgh die? No. A couple of Strepsils will do the job."

Don Martin should put his fedora back on.

And what you don't know can kill you...

Sunday, April 26, 2009

Swine Flu and the Echo of 1918














As the swine flu continues to spread around the world.

The billion dollar question is why is it so mild in most places and so deadly in Mexico?

It may be that we simply don't have enough cases to get a proper picture of the outbreak. It could be the virus is fizzling out...which H1N1 viruses often do as they pass from person to person.

Or it could be an echo of the Spanish flu of 1918. Which was mild when it first arrived in the Spring of that year. And deadly by the fall.












This old chart shows how the virus suddenly mutated into a killer. One that caused the immune systems of young and healthy patients to go into overdrive. Which also seems to be happening in Mexico and is another echo of 1918.

And the question is whether the virus has been in Mexico long enough to trigger a second wave...or whether the deaths are just a wrong turn for the virus as it mutates into a milder form. And learns to live with its hosts instead of killing them.

The problem is the longer these kind of viruses are out there unchecked by herd immunity, the more likely it is that they might mutate into a more lethal form, or swap genes with something like the Bird Flu virus....and that could be disastrous. Because while the Spanish Flu had an average mortality rate of 2.5 %....and the mortality rate of this virus is slightly higher....the Avian flu has a mortality rate of about fifty per cent.

The good news is that we should be able to answer these questions in a matter of days. And that whatever happens we are infinitely better prepared to deal with a pandemic than we were in 1918.

We have antibiotics, we have ventilators, we have new anti-viral drugs. Thanks to SARS and the Avian flu scare we also have all kinds of plans to deal with an emergency situation.

And above all there is an army of men and women in green and white who have been preparing for years to fight this battle. And we're READY.

So the only thing to fear is fear itself. And if we all do what we have to do.

We can still beat this bug....